Search for: All records

Objective To determine if natural language processing (NLP) and machine learning (ML) techniques accurately identify interview-based psychological stress and meaning/purpose data in child/adolescent cancer survivors. Materials and Methods Interviews were conducted with 51 survivors (aged 8-17.9 years; ≥5-years post-therapy) from St Jude Children’s Research Hospital. Two content experts coded 244 and 513 semantic units, focusing on attributes of psychological stress (anger, controllability/manageability, fear/anxiety) and attributes of meaning/purpose (goal, optimism, purpose). Content experts extracted specific attributes from the interviews, which were designated as the gold standard. Two NLP/ML methods, Word2Vec with Extreme Gradient Boosting (XGBoost), and Bidirectional Encoder Representations from Transformers Large (BERTLarge), were validated using accuracy, areas under the receiver operating characteristic curves (AUROCC), and under the precision-recall curves (AUPRC). Results BERTLarge demonstrated higher accuracy, AUROCC, and AUPRC in identifying all attributes of psychological stress and meaning/purpose versus Word2Vec/XGBoost. BERTLarge significantly outperformed Word2Vec/XGBoost in characterizing all attributes (P <.05) except for the purpose attribute of meaning/purpose. Discussion These findings suggest that AI tools can help healthcare providers efficiently assess emotional well-being of childhood cancer survivors, supporting future clinical interventions. Conclusions NLP/ML effectively identifies interview-based data for child/adolescent cancer survivors. 

Theoretical and empirical comparisons have been made to assess the expressive power and performance of invariant and equivariant GNNs. However, there is currently no theoretical result comparing the expressive power of k-hop invariant GNNs and equivariant GNNs. Additionally, little is understood about whether the performance of equivariant GNNs, employing steerable features up to type-L, increases as L grows – especially when the feature dimension is held constant. In this study, we introduce a key lemma that allows us to analyze steerable features by examining their corresponding invariant features. The lemma facilitates us in understanding the limitations of k-hop invariant GNNs, which fail to capture the global geometric structure due to the loss of geometric information between local structures. Furthermore, we analyze the ability of steerable features to carry information by studying their corresponding invariant features. In particular, we establish that when the input spatial embedding has full rank, the informationcarrying ability of steerable features is characterized by their dimension and remains independent of the feature types. This suggests that when the feature dimension is constant, increasing L does not lead to essentially improved performance in equivariant GNNs employing steerable features up to type-L. We substantiate our theoretical insights with numerical evidence.